• 목록
• 답변
• 글쓰기
• 게시판 리스트 옵션
  • 수정
  • 삭제

Depression Treatment Advancements

Researchers are constantly striving to improve the treatment for depression. This special Research in Context feature will look at some of these depression treatment advancements.

Psychotherapy can help alleviate depression symptoms by teaching a person how to deal with negative feelings and thoughts. Talk therapy can be conducted in an environment of group or one-on-one with a mental health professional.

Precision mental healthcare

The term "precision" refers to bringing more exactness or accuracy to diagnosis, prevention and treatment methods. In the context of mental health, it can encompass a variety of strategies, from medication to psychotherapy. Many of these strategies concentrate on the symptoms of the disorder, rather than the root causes. This can result in treatments that do nothing more than ease symptoms, but do not address the underlying factors that lead to mental illness in the initial place.

Precision mental healthcare is rapidly improving. It's similar to the method that's been taken in other areas of healthcare by incorporating continuous monitoring of vital indicators into clinical practice (e.g. fever, temperature or blood pressure). It also includes combining multiple sources of data and applying machine learning to help physicians better understand a patient's specific needs and create more efficient treatment strategies.

One example of precision psychiatry involves using EEG to measure brain activity and assist doctors determine whether a patient is able to engage in cognitive behavior therapy. A new class of medications known as NMDA receptor inhibitors can reduce seasonal depression treatment symptoms by preventing the neurotransmitter, glutamate, from reaching specific brain cells. Another possible breakthrough is the use of pharmacogenetic testing to identify drug-gene interactions and to avoid adverse side effects.

A number of companies are also experimenting with digital precision medicine, which utilizes objective digital technology to monitor patients remotely and collect real-time data that aids in their treatment. For example, one company is leveraging artificial intelligence to track adherence and optimize medication dosages for patients suffering from depression. These solutions have the possibility of improving accessibility and effectiveness in mental health care and also enhancing adherence to treatment.

Digital precision psychiatry in particular it is a way to help people suffering from mental illness overcome barriers to treatment, especially those who are employed. Johnson & Johnson, for instance, is working with organizations in Singapore to help facilitate the reintegration of people recovering from depression treatment centres back into their workplaces. This can help them maintain their jobs, which is essential for mental health recovery.

Medication

Many people suffering from depression treatment for elderly discover that medication can alleviate their symptoms, particularly if they're experiencing severe or disabling symptoms. Antidepressants help restore the balance of neurotransmitters in the brain, which are chemical messengers that regulate mood and emotion. Most antidepressants focus on one of these neurotransmitters, boosting levels of serotonin, norepinephrine, and dopamine. Selective serotonin Reuptake inhibitors (SSRIs) like Prozac and Zoloft increase the amount of the serotonin chemical in the brain. Serotonin reuptake inhibitors, such as Cymbalta and Effexor are able to focus on both dopamine and norepinephrine and monoamine oxidase inhibiters, such as Wellbutrin, target only norepinephrine and dopamine.

Most doctors prescribe antidepressants in order to treat depression as a first treatment, in addition to talk therapy. Some of these treatments include cognitive therapy that helps improve thoughts and feelings by educating specific skills or psychotherapy for interpersonal relations, which focuses on improving relationships. Other treatments, like electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are also known to have been proven to be effective in treating depression.

Unfortunately, some people do not respond to the first medication prescribed by doctors. Up to one-third of people suffering from depression do not receive relief from the first medication they take, and 40 percent of people who start taking antidepressants discontinue them within three months. The good news is that research has allowed doctors to predict which kind of medication is most effective for each person, using blood or MRI tests to determine which receptors are most affected by depression.

Medication has improved in recent years, with a wider range of options and higher dosages to minimize negative effects. Newer antidepressants such as esketamine, brexanolone and nefazodone work to quickly alleviate depression symptoms.

Other medications are undergoing clinical trials that could change the ways they're used. Vorapaxar, a drug which is currently being tested in humans, targets a distinct part of the brain that's associated with depression, by blocking NMDA receptors. It's scheduled to be available by 2024. A combination of ketamine with bupropion has also demonstrated potential. It may be more effective in Treating depression Without antidepressants depression that is resistant to treatment.

Psychotherapy

Psychologists have identified certain factors that can cause depression. These include imbalances of the neurotransmitters norepinephrine and serotonin. These chemicals are vital in regulating mood and emotions, as in the overall function of the brain. Medications such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors are the main treatment options. They can alleviate many of depression-related symptoms, including depressed feelings and fatigue, and improve appetite, sleep and energy levels. They do not come without adverse effects, which could cause them to be unsuitable for some people.

Psychotherapy can help address the root causes and help individuals overcome depression. Different types of therapy have been proven to reduce symptoms, such as cognitive behavioral therapy and the ketamine infusion therapy. Psychotherapy can help people to develop a healthier way of coping and manage stressors better. However access to psychotherapy may be limited due to cost, scheduling limitations, and a shortage of mental health providers. Telehealth services have made it easier for many people.

Finding the best treatment combination is the key to beating private depression treatment. The use of medication alone isn't enough to relieve all of your symptoms, and it can take 6 to 12 weeks before you know whether a medication is effective. There are many nonpharmacologic treatments options, including transcranial magnetic stimulation that is repeated and vagus nerve stimulation. These treatments employ electromagnetic fields to stimulate the brain's natural chemical and enhance mood.

It's crucial to collaborate closely with your provider, whether you're looking to try therapy or medication. Discuss your thoughts and feelings about the risks and side effects that come with each choice. Find a provider that can meet your needs if you are having trouble getting trust from your doctor or therapist. A service that provides a trial period free of charge could be a great option, as it offers you the opportunity to try different options before making a commitment. You'll eventually find a treatment that is effective for you and makes you feel better.

Brain stimulation

In a few short years, scientists have come up with new methods to target specific regions of the brain and swiftly change how they function. These techniques can also be used to treat physical ailments as well as some mental disorders.

rTMS is a technique which utilizes electromagnetic pulses to stimulate brain activity. It is similar to the magnetic pulses that are used in MRIs, but not sufficient to trigger seizures. The method works by stimulating a specific area of the head with a non-painful magnet. The pulses affect the way that brain signals are processed and allows you to feel better. The treatment could take just 3.5 minutes and isn't a problem with your everyday activities. You may feel a slight headache afterwards.

Another treatment involves putting electrodes into the brain to send electrical zaps. This procedure is also referred to as deep transcranial magnetic stimulation (deep TMS) and is used for OCD and to stop smoking cigarettes. Initial studies suggest that it could alleviate depression symptoms in certain individuals. It's not clear how this treatment works, but it appears to alter the balance of certain Neurotransmitters.

Other types of noninvasive brain stimulation are also advancing as well. For instance, a recent study found that patients suffering from severe depression who were resistant to antidepressants responded to a magnetic treatment called SAINT. It's customized to the specific anatomy of each patient's brain and utilizes high-dose patterns of magnetic pulses. The treatment is delivered in just a few hours, while previous treatments required regular sessions for months or weeks.

Researchers utilized fMRI technology to pinpoint the exact brain area that was being stimulated by each patient. They also examined the small differences in the way that the brain's different regions were activated which allowed them to discern the direction of the signals. They discovered that the anterior cingulate cortex sent signals to the subgenual cortex in depressed people. These messages were frequently not directed correctly. The more severe depression the more signals were directed in the wrong direction.